Christina Applegate’s heartbreaking health battle is taking a frightening new turn — and insiders say those closest to her are bracing for the worst.
The beloved actress, who was diagnosed with multiple sclerosis in 2021, has reportedly been hospitalized since late March, sparking fresh concern among friends who say her condition has become increasingly unpredictable and “hellish” behind the scenes.
Sources close to the 54-year-old star say her inner circle is trying to stay hopeful — but privately, fears are growing.
“With every setback, if we’re being honest, it’s in the back of everyone’s mind that there might not be a tomorrow with her,” one insider revealed, painting a grim picture of the emotional toll her illness is taking on those around her.
Despite the devastating progression of the disease, Applegate is still fighting — but it hasn’t been easy.
Friends describe a brutal cycle of ups and downs, with no real “good days” anymore — only moments where things feel slightly less overwhelming. “She’s a fighter,” the source said. “But this has been treacherous. It’s something she’s constantly battling.”
The toll isn’t just physical — it’s deeply emotional.
In a candid 2024 podcast appearance, Applegate didn’t sugarcoat her reality, admitting, “I don’t enjoy living. I don’t enjoy things anymore.” Those close to her now fear her mental state may be even more fragile as her health struggles continue.
Still, those around her aren’t giving up.
“She’s in rough shape, but nobody is acting like this is the end,” the insider added. “People believe in her doctors and, more importantly, in her will to keep going.”
Her recently released memoir revealed even more shocking details about what she’s endured — including a dramatic 50-pound weight loss that she described as both “dangerous” and “scary.”
At one point, the transformation was so extreme she avoided mirrors entirely for nearly a year.
Applegate explained that severe stomach issues linked to MS forced her onto a restrictive diet — triggering the rapid drop in weight. “Within seven months, it was all gone,” she shared, noting her legs have become so thin they no longer resemble her own.
And even something as simple as eating has become a risk.
She revealed that indulging in foods she craves could land her back in the emergency room — something that has already happened multiple times in recent months.
“The illness has given me serious stomach issues,” she said, describing the painful trade-offs she now faces daily.
Still, in true Christina fashion, there’s a quiet defiance beneath the pain.
Even as her body changes and the disease continues its relentless progression, she’s determined not to let it define her entirely.
There’s still a voice in her head pushing back — reminding her that she’s still here, still fighting… even as the battle grows tougher by the day.
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God help her